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BDBM50455914 CHEMBL7615

SMILES: CC(=O)c1c(C2=NCC3(CN4CCC3CC4)O2)c2ccccc2n1C

InChI Key: InChIKey=NDFOPAVNAMMDDL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455914   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50455914
PNG
(CHEMBL7615)
Show SMILES CC(=O)c1c(C2=NCC3(CN4CCC3CC4)O2)c2ccccc2n1C
Show InChI InChI=1S/C20H23N3O2/c1-13(24)18-17(15-5-3-4-6-16(15)22(18)2)19-21-11-20(25-19)12-23-9-7-14(20)8-10-23/h3-6,14H,7-12H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Q-ICS-205-930 from 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes


J Med Chem 35: 1019-31 (1992)


Article DOI: 10.1021/jm00084a007
BindingDB Entry DOI: 10.7270/Q2833THX
More data for this
Ligand-Target Pair