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BDBM50455924 CHEMBL276728

SMILES: [H][C@@]12CC[N@@](C1)C[C@@]21CN=C(O1)c1cn(C)c2ccccc12

InChI Key: InChIKey=DGWZAHMLMHDYQK-PXAZEXFGSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50455924   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor


(Rattus norvegicus-RAT)
BDBM50455924
PNG
(CHEMBL276728)
Show SMILES Cn1cc(C2=NC[C@@]3(C[N@]4CC[C@@H]3C4)O2)c2ccccc12
Show InChI InChI=1S/C17H19N3O/c1-19-9-14(13-4-2-3-5-15(13)19)16-18-10-17(21-16)11-20-7-6-12(17)8-20/h2-5,9,12H,6-8,10-11H2,1H3/t12-,17+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]Q-ICS-205-930 from 5-hydroxytryptamine 3 receptor recognition sites in rat brain membranes


J Med Chem 35: 1019-31 (1992)


Article DOI: 10.1021/jm00084a007
BindingDB Entry DOI: 10.7270/Q2833THX
More data for this
Ligand-Target Pair