BDBM50457310 CHEMBL4218285
SMILES CNC(=O)c1ccc(C)c(Nc2nccc(n2)-c2cc3c(NC[C@]3(C)CO)c(c2)C#N)c1
InChI Key InChIKey=AZLAULHUEAUCSF-XMMPIXPASA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50457310
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant human GST-tagged MAP3K14 autophosphorylation after 1 hr by Alpha screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of MAP3K14 in human L363 assessed as decrease in IKKalpha phosphorylation level after 2 hrs by sandwich immuno assayMore data for this Ligand-Target Pair