BDBM50457315 CHEMBL4210340::US10662187, Compound 105::US10793566, Compound 105
SMILES CC#CC(=O)N1CCC[C@H](C1)n1nc(-c2ccc(cc2)C(=O)Nc2ccccn2)c2cnccc12
InChI Key InChIKey=GWSWYVDRDVOKTP-OAQYLSRUSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50457315
Affinity DataIC50: 100nMAssay Description:Inhibition of BTK (unknown origin) using peptide substrate after 1 hr by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Measurements were performed in a reaction volume of 15 μL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 μM peptide subst...More data for this Ligand-Target Pair