BDBM50459225 CHEMBL4211060

SMILES OC(=O)c1noc(c1-c1cccc(c1)-c1ccc(O)c(Cl)c1)-c1ccccc1

InChI Key InChIKey=BYSLNSJAOMQGCJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50459225   

TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis)
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459225(CHEMBL4211060)
Affinity DataIC50:  900nMAssay Description:Inhibition of Mycobacterium tuberculosis H37Rv His-tagged ptpB expressed in Escherichia coli BL21(DE3) using pNPP as substrate preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDual specificity protein phosphatase 3(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459225(CHEMBL4211060)
Affinity DataIC50:  1.87E+4nMAssay Description:Inhibition of human VHR using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50459225(CHEMBL4211060)
Affinity DataIC50:  2.13E+5nMAssay Description:Inhibition of human PTP1B using pNPP as substrate preincubated for 15 mins followed by substrate addition and measured after 15 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed