BDBM50459898 CHEMBL4227907
SMILES CN(CCCNc1nc(Nc2ccc(OCCCOCCCCOCCCOCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(cc3)-c3scnc3C)C(C)(C)C)cc2)ncc1Br)C(=O)C1CCC1
InChI Key InChIKey=QMGHHBHPDDAGGO-IIWOMYBWSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50459898
Affinity DataKd: 4.60nMAssay Description:Binding affinity to human full length wild-type TBK1 expressed in mammalian expression systemMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TBK1 (unknown origin)More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of IKKepsilon (unknown origin)More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit epsilon(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataKd: 70nMAssay Description:Binding affinity to human full length wild-type IKKepsilon expressed in mammalian expression systemMore data for this Ligand-Target Pair
TargetElongin-B/Elongin-C/Hypoxia-inducible factor 1-alpha/von Hippel-Lindau disease tumor suppressor(Homo sapiens (Human))
Arvinas
Curated by ChEMBL
Arvinas
Curated by ChEMBL
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of His-tagged VHL/elongin B/elongin C (unknown origin) interaction with HIF1alpha preincubated for 10 mins followed by fluorescin labelled...More data for this Ligand-Target Pair