BDBM50460104 CHEMBL4224807

SMILES CN([C@@H]1CCN(C1)C(=O)CC#N)c1ncnc2[nH]ccc12

InChI Key InChIKey=NSQLMHCVPLHMQU-SNVBAGLBSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50460104   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50460104(CHEMBL4224807)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant human JAK2 (808-end residues) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50460104(CHEMBL4224807)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human JAK1 (866-end residues) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50460104(CHEMBL4224807)
Affinity DataIC50:  9.30E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by automated patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50460104(CHEMBL4224807)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant human JAK3 (781-end residues) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50460104(CHEMBL4224807)
Affinity DataIC50:  110nMAssay Description:Inhibition of recombinant human TYK2 (875-end residues) in presence of ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed