BDBM50461073 CHEMBL4226140::US10457637, Compound 48

SMILES CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc(OC2CCN(CC2)S(C)(=O)=O)c(c1)S(C)(=N)=O

InChI Key InChIKey=WQXWSUZBSKGNPR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50461073   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50461073(CHEMBL4226140 | US10457637, Compound 48)
Affinity DataIC50: >1.00E+3nMAssay Description:The RORγ transactivation model was developed from the line HG5LN, which is a HeLa line that stably expresses a luciferase reporter gene controll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Galderma Research & Development

US Patent
LigandPNGBDBM50461073(CHEMBL4226140 | US10457637, Compound 48)
Affinity DataIC50:  6.40E+3nMAssay Description:Inverse agonist activity at RORgamma (unknown origin) expressed in human HeLa-derived HG5LN cells transfected with the GAL4 DNA-binding domain fused ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed