BDBM50464112 CHEMBL4248589

SMILES OC(=O)C[C@H](CN1CC[C@@H](CCc2ccc3CCCNc3n2)C1)c1cc(cc(c1)N1CCOCC1)C1CC1

InChI Key InChIKey=OGWLKQKCWNAXLA-AJTFRIOCSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50464112   

TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464112(CHEMBL4248589)
Affinity DataKi:  0.0794nMAssay Description:Binding affinity to alphaVbeta6 (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464112(CHEMBL4248589)
Affinity DataIC50:  2.00E+3nMAssay Description:Antagonist activity at human integrin alphaVbeta3 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-8(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464112(CHEMBL4248589)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human integrin alphaVbeta8 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464112(CHEMBL4248589)
Affinity DataIC50: <6.31E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells by Barracuda automated patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464112(CHEMBL4248589)
Affinity DataIC50:  63nMAssay Description:Antagonist activity at human integrin alphaVbeta1 expressed in human A549 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-6(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464112(CHEMBL4248589)
Affinity DataIC50:  4nMAssay Description:Antagonist activity at human integrin alphaVbeta6 expressed in human K562 cells assessed as reduction in cell adhesion to GST-LAP after 30 mins by BC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-5(Homo sapiens (Human))
University Of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50464112(CHEMBL4248589)
Affinity DataIC50:  200nMAssay Description:Antagonist activity at human integrin alphaVbeta5 expressed in human K562 cells assessed as reduction in cell adhesion to vitronectin after 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed