BDBM50464926 CHEMBL4288572

SMILES NC(=O)c1cc(F)cc2[nH]c(nc12)-c1cc2CCNCc2o1

InChI Key InChIKey=BLVQSAHMDXWBNC-UHFFFAOYSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50464926   

TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50464926(CHEMBL4288572)
Affinity DataKd:  180nMAssay Description:Binding affinity to PARP1 (unknown origin) by ITCMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPoly [ADP-ribose] polymerase 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50464926(CHEMBL4288572)
Affinity DataIC50:  244nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPoly [ADP-ribose] polymerase 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50464926(CHEMBL4288572)
Affinity DataIC50:  144nMAssay Description:Inhibition of recombinant human PARP2 using histone as substrate after 1.5 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed