BDBM50465078 CHEMBL4293906

SMILES [H][C@]12CC[C@]([H])(CN(C1)c1cc(C)ncn1)[C@H]2Nc1nc(NC)c2c(n1)N(CCC2(C)C)c1ccc(F)cc1

InChI Key InChIKey=QFTDIWBBGLTDFH-NHKMSHSESA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50465078   

TargetPresenilin-1(Homo sapiens (Human))
Temple University School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50465078(CHEMBL4293906)
Affinity DataEC50:  35nMAssay Description:Inhibition of gamma-secretase (unknown origin) assessed as reduction in amyloid beta (1 to 42) production after 60 mins by cell based AlphaLisa assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed