BDBM50467368 CHEMBL4294551

SMILES CSc1ncc2c(Nc3n[nH]c(C)c3N=C2c2ccc(C)cc2)n1

InChI Key InChIKey=YDPCOTOJRODRFO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467368   

TargetAurora kinase B(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467368(CHEMBL4294551)
Affinity DataIC50:  100nMAssay Description:Inhibition of Aurora B (unknown origin) using STK S2 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467368(CHEMBL4294551)
Affinity DataIC50:  71nMAssay Description:Inhibition of Aurora A (unknown origin) using STK S2 as substrate after 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467368(CHEMBL4294551)
Affinity DataIC50:  157nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged KDR (790 to end residues) expressed in baculovirus infected Sf21 insect cells after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed