BDBM50467368 CHEMBL4294551
SMILES CSc1ncc2c(Nc3n[nH]c(C)c3N=C2c2ccc(C)cc2)n1
InChI Key InChIKey=YDPCOTOJRODRFO-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50467368
Affinity DataIC50: 100nMAssay Description:Inhibition of Aurora B (unknown origin) using STK S2 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 71nMAssay Description:Inhibition of Aurora A (unknown origin) using STK S2 as substrate after 40 mins by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
East China Normal University
Curated by ChEMBL
East China Normal University
Curated by ChEMBL
Affinity DataIC50: 157nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged KDR (790 to end residues) expressed in baculovirus infected Sf21 insect cells after 60 mins by...More data for this Ligand-Target Pair