BDBM50467370 CHEMBL4278759

SMILES CCN(CC)c1ncc2c(Nc3n[nH]c(C)c3N=C2c2ccc(C)cc2)n1

InChI Key InChIKey=LVJOSXIHDWKFCU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467370   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467370(CHEMBL4278759)
Affinity DataIC50:  8.30nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged KDR (790 to end residues) expressed in baculovirus infected Sf21 insect cells after 60 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467370(CHEMBL4278759)
Affinity DataIC50:  269nMAssay Description:Inhibition of Aurora A (unknown origin) using STK S2 as substrate after 40 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50467370(CHEMBL4278759)
Affinity DataIC50:  322nMAssay Description:Inhibition of Aurora B (unknown origin) using STK S2 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed