BDBM50473628 CHEMBL307604::RPR-235315

SMILES COCCNC(=O)[C@]1(C)CO[C@@H](OC1)c1nc(c([nH]1)-c1ccnc(NCC=C)n1)-c1ccc(F)cc1

InChI Key InChIKey=JNRDQHFKWJTGMW-WZJNIGMMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473628   

TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50473628(CHEMBL307604 | RPR-235315)
Affinity DataIC50:  73nMAssay Description:Inhibition of p38-related TNF alpha release by human monocyte cell line (THP-1)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 13(Mus musculus)
Aventis Pharma

Curated by ChEMBL
LigandPNGBDBM50473628(CHEMBL307604 | RPR-235315)
Affinity DataIC50:  62nMAssay Description:Inhibition of murine Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed