BDBM50475982 CHEMBL215375

SMILES CC[C@H]1OC(O)=C2[C@@H](C3=C(COCC3=O)N=C12)c1ccc(F)c(Br)c1

InChI Key InChIKey=UTHUTBNOTJCXJO-ZIAGYGMSSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50475982   

LigandPNGBDBM50475982(CHEMBL215375)
Affinity DataEC50:  169nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475982(CHEMBL215375)
Affinity DataEC50:  19nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax spontaneous bladder contractionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475982(CHEMBL215375)
Affinity DataEC50:  2.95E+3nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475982(CHEMBL215375)
Affinity DataEC50:  170nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475982(CHEMBL215375)
Affinity DataEC50:  281nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475982(CHEMBL215375)
Affinity DataEC50:  7.24E+3nMAssay Description:Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50475982(CHEMBL215375)
Affinity DataEC50:  282nMAssay Description:Activity against pig bladder KATP channel opening assessed as ability to relax field-stimulated pig detrusorMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed