BDBM50477915 CHEMBL252846

SMILES C[C@H](CCCn1ccnn1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=HNASCYSOMXPHHP-OAHLLOKOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477915   

TargetPresenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50477915(CHEMBL252846)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human gamma secretase in H4 cells assessed as reduction of amyloid beta-40 levelsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed