BDBM50491472 CHEMBL2368566

SMILES FCC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

InChI Key InChIKey=CAILNONEKASNSH-ZEQRLZLVSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50491472   

TargetProcathepsin L(Human)
Cha University

Curated by ChEMBL
LigandPNGBDBM50491472(CHEMBL2368566)
Affinity DataIC50:  84nMAssay Description:Inhibition of cathepsin L (unknown origin) using Z-FR-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cha University

Curated by ChEMBL
LigandPNGBDBM50491472(CHEMBL2368566)
Affinity DataIC50:  66nMAssay Description:Inhibition of cathepsin B (unknown origin) using RR-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin B(Human)
Cha University

Curated by ChEMBL
LigandPNGBDBM50491472(CHEMBL2368566)
Affinity DataIC50:  66nMAssay Description:Inhibition of cathepsin B (unknown origin) using RR-AMC as substrate preincubated for 30 mins followed by substrate addition and further incubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCalpain-1 catalytic subunit(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50491472(CHEMBL2368566)
Affinity DataIC50:  397nMAssay Description:Inhibition of human erythrocytes mu-calpain using Pep1 as substrate incubated for 30 mins under shaking condition in presence of CaCl2 by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProcathepsin L(Human)
Cha University

Curated by ChEMBL
LigandPNGBDBM50491472(CHEMBL2368566)
Affinity DataIC50:  84nMAssay Description:Inhibition of cathepsin L (unknown origin) using Z-FR-AMC as substrate preincubated for 30 mins followed by substrate addition and further incubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed