BDBM50499005 CHEMBL3736365

SMILES COC1CCN(CC1)c1nccc(Nc2cc3n(cnc3cn2)C(C)C(F)(F)F)n1

InChI Key InChIKey=SPPAJTSZHAHTMB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499005   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50499005(CHEMBL3736365)
Affinity DataKi:  27nMAssay Description:Inhibition of human EGFR T790M/L858R double mutant using Fl-EEPLYWSFPAKKK-CONH2 as substrate preincubated for 30 mins followed by addition of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed