BDBM50499736 CHEMBL3740601
SMILES NC(=O)C[C@H](NC(=O)[C@@H]1CCCN1S(=O)(=O)c1ccc(cc1)-c1ccccc1)C#N
InChI Key InChIKey=YWRRVZYQZWHQKZ-HKUYNNGSSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50499736
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human legumain using Z-Ala-Ala-Asn-MCA substrate measured every 2 mins for 60 mins by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant cathepsin B (unknown origin) using Z-Leu-Arg-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant caspase 3 (unknown origin) using DEVD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant cathepsin S (unknown origin) using ZVVR-AMC fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of recombinant caspase 8 (unknown origin) using IETD-AFC fluorogenic substrateMore data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase 17(Homo sapiens)
Queen'S University Belfast
Curated by ChEMBL
Queen'S University Belfast
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of USP17 in human HEK293T cells using fluorogenic substrate ub-rhodamine110 preincubated for 30 mins followed by substrate addition measur...More data for this Ligand-Target Pair