BDBM50500965 CHEMBL3799372

SMILES CN1CCN(CCOc2nn(-c3ccccc3F)c3ccc(F)cc23)C1=O

InChI Key InChIKey=MFXGWJILJOSHLE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500965   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500965(CHEMBL3799372)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293F cells measured at -65 mV holding potential by Qpatch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500965(CHEMBL3799372)
Affinity DataIC50:  320nMAssay Description:Inhibition of recombinant human Nav1.7 expressed in HEK293F cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed