BDBM50500979 CHEMBL3798254

SMILES COc1cc(C)c(CNC[C@@H](NC(=O)c2cc(C)on2)c2ccccc2)cc1C

InChI Key InChIKey=JWARISOWNKYPRB-OAQYLSRUSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500979   

TargetSphingosine-1-phosphate lyase 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500979(CHEMBL3798254)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of wild-type full-length human sphingosine 1-phosphate lyase transfected in HEK293-H cells preincubated for 30 mins followed by addition o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetSphingosine-1-phosphate lyase 1(Human)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50500979(CHEMBL3798254)
Affinity DataIC50:  485nMAssay Description:Inhibition of human sphingosine 1-phosphate lyase after 22 hrs by umbelliferone fluorescence analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed