BDBM50504091 CHEMBL4575618

SMILES CC(=O)NCCNCc1cc(C)c(OCc2cccc(c2C)-c2cccc(COc3cc(OCc4cncc(c4)C#N)c(CNCCNC(C)=O)cc3C)c2C)cc1OCc1cncc(c1)C#N

InChI Key InChIKey=RNCINFJGGSQEHN-UHFFFAOYSA-N

Data  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50504091   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504091(CHEMBL4575618)
Affinity DataIC50:  3nMAssay Description:Inhibition of human Fc-tagged PD1 N-terminal domain (Leu25 to Gln167 residues) expressed in HEK293 cells/human His-tagged PDL1 (Phe19 to Arg238 resid...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504091(CHEMBL4575618)
Affinity DataIC50:  3nMAssay Description:Inhibition of human PD-1/PD-L1 interaction by HTRF binding assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504091(CHEMBL4575618)
Affinity DataEC50:  79nMAssay Description:Inhibition of PD1/PDL1 interaction in human Jurkat cells co-cultured with human U2OS cells expressing PDL1 assessed as reduction in SHP1 recruitment ...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand/protein 1(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50504091(CHEMBL4575618)
Affinity DataEC50:  763nMAssay Description:Inhibition of human PD1 stably expressed in human Jurkat T cells co-expressing NFAT-induced luciferase/human PDL1 stably expressed in CHOK1 cells co-...More data for this Ligand-Target Pair