BDBM50506115 CHEMBL4463626

SMILES Clc1cccc(Cc2c([nH]c3ncnn3c2=O)C2CC2)c1

InChI Key InChIKey=OTRWOBVXEPACEI-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50506115   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506115(CHEMBL4463626)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506115(CHEMBL4463626)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50506115(CHEMBL4463626)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at CCR2b in human THP1 cells assessed as inhibition of human MCP1 induced calcium flux by fluo-4 dye based fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed