BDBM50506158 CHEMBL4521594
SMILES NS(=O)(=O)c1cc(NC(=O)Cc2ccccc2)ccc1Oc1cccc(Cl)c1
InChI Key InChIKey=CSJYMAFXYMYNCK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50506158
Affinity DataIC50: 108nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of Mg-ATP-induced calcium influx incubated for 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 211nMAssay Description:Antagonist activity at human P2X4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 233nMAssay Description:Antagonist activity at rat P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of Mg-ATP-induced calcium influx incubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Antagonist activity at mouse P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of Mg-ATP-induced calcium influx incubated for 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Antagonist activity at human P2X1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Antagonist activity at human P2X3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+4nMAssay Description:Antagonist activity at human P2X7 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 211nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in HEK293 cells assessed as inhibition of Bz-ATP-induced calcium influx incubated for 30 mins a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Antagonist activity at human P2X2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.17E+3nMAssay Description:Antagonist activity at human DAT receptor by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human P2X4 receptor tranfected in human 1321N1 cells assessed as inhibition of inhibition of ATP-evoked current at -90 mV hold...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of carbonic anhydrase 2 (unknown origin)More data for this Ligand-Target Pair