BDBM50508561 CHEMBL4448768
SMILES CC(=O)N1CC(C1)NC(=O)c1ccncc1Nc1cc(-c2ccc3ccn(C)c3c2)c2nccnc2c1
InChI Key InChIKey=DSMWVAJEDQCPPQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50508561
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita
Curated by ChEMBL
Selvita
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of recombinant human His-tagged PFKFB3 expressed in Escherichia coli using fructose-6-phosphate as substrate measured after 2 hrs by ADP-G...More data for this Ligand-Target Pair
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3(Homo sapiens (Human))
Selvita
Curated by ChEMBL
Selvita
Curated by ChEMBL
Affinity DataIC50: 9.74E+4nMAssay Description:Inhibition of PFKFB3 in human HCT116 cell lysates assessed as reduction in glycolytic-flux induced fructose-2,6-bisphosphate formation using fructose...More data for this Ligand-Target Pair