BDBM5051 5-Chloro-N-(4-chloro-5-isopropyl-3-methyl-13-thiazol-2(3H)-ylidene)-2-hydroxybenzenesulfonamide::5-chloro-N-[(2Z)-4-chloro-3-methyl-5-(propan-2-yl)-2,3-dihydro-1,3-thiazol-2-ylidene]-2-hydroxybenzene-1-sulfonamide::thiazolidenebenzenesulfonamide deriv. 11f

SMILES CC(C)c1s\c(=N/S(=O)(=O)c2cc(Cl)ccc2O)n(C)c1Cl

InChI Key InChIKey=VTKAGCUSZSWYBW-SSZFMOIBSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 5051   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5051(5-Chloro-N-(4-chloro-5-isopropyl-3-methyl-13-thiaz...)
Affinity DataIC50:  9.40nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Korea Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM5051(5-Chloro-N-(4-chloro-5-isopropyl-3-methyl-13-thiaz...)
Affinity DataIC50:  158nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5051(5-Chloro-N-(4-chloro-5-isopropyl-3-methyl-13-thiaz...)
Affinity DataIC50:  21nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5051(5-Chloro-N-(4-chloro-5-isopropyl-3-methyl-13-thiaz...)
Affinity DataIC50:  170nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed