BDBM50519610 CHEMBL4533049
SMILES OC(=O)c1ccc2OC[C@H](CN(CC3CCC3)c2c1)c1ccc(Cl)cc1Cl
InChI Key InChIKey=FLTAOBQLOVJBJL-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50519610
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Caen Normandy
Curated by ChEMBL
University of Caen Normandy
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of TAMRA-labeled BIM BH3 peptide binding to human Mcl1 (171 to 327 residues) incubated for 120 mins by fluorescence polarizationMore data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Caen Normandy
Curated by ChEMBL
University of Caen Normandy
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of MCL1 (unknown origin)More data for this Ligand-Target Pair
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Caen Normandy
Curated by ChEMBL
University of Caen Normandy
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant His6-tagged human MCL1 (171 to 327 residues) expressed in Escherichia coli and TAMRA labeled Bim BH3 peptide interaction us...More data for this Ligand-Target Pair