BDBM50524277 CHEMBL4451741

SMILES CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1

InChI Key InChIKey=GJCLSMLUWFQTQP-NZTKNTHTSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50524277   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524277(CHEMBL4451741)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of 20S proteasome beta5 subunit in human RPMI8226 cell lysate using Suc-LLVY-AMC as substrate pretreated for 1 hr followed by substrate ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50524277(CHEMBL4451741)
Affinity DataIC50:  744nMAssay Description:Inhibition of purified human 20S immunoproteasome beta1 subunit using Ac-Pro-Ala-Leu-AMC as substrate pretreated for 1 hr followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed