BDBM50524991 CHEMBL4544243::US11401286, Example 57
SMILES CCc1nc(Nc2ccc(CC(N)=O)cc2)nc(n1)-c1cccc(Cl)c1
InChI Key InChIKey=GVEYRZKCFLDNIU-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50524991
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Tetra Discovery Partners
Curated by ChEMBL
Tetra Discovery Partners
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant human His6-tagged PDE4B1 UCR1 S133D mutant expressed in baculovirus infected Sf9 insect cells using cAMP as substrate prein...More data for this Ligand-Target Pair
TargetIsoform 7 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Tetra Discovery Partners
US Patent
Tetra Discovery Partners
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D7 [S54D](Human)
Tetra Discovery Partners
US Patent
Tetra Discovery Partners
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B [S133D](Human)
Tetra Discovery Partners
US Patent
Tetra Discovery Partners
US Patent
Affinity DataIC50: <1.00E+3nMAssay Description:Assays are performed in 96-well plates in a total volume of 200 μl/well. Compounds are dissolved in dimethylsulfoxide (DMSO) and added to plates...More data for this Ligand-Target Pair