BDBM50534356 CHEMBL4554886

SMILES Cc1cc(ccn1)[C@@H]1CC[C@H](CO1)Nc1ncc2OCCN(c3ccccc3Cl)c2n1

InChI Key InChIKey=CPDNCFLPZBNZCX-XLIONFOSSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534356   

TargetPresenilin-1(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50534356(CHEMBL4554886)
Affinity DataEC50:  41nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed