BDBM50534364 CHEMBL4519705

SMILES COc1cc(Nc2ncc3OCC4(CC4)N(C)c3n2)ccc1-n1cnc(C)c1

InChI Key InChIKey=HJOVHXDSQZWCLA-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50534364   

TargetPresenilin-1(Homo sapiens (Human))
Forum Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50534364(CHEMBL4519705)
Affinity DataEC50:  49nMAssay Description:Modulation of gamma-secretase in human H4 cells expressing human APP751 assessed as reduction in amyloid beta 42 production after 16 to 18 hrs by san...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed