BDBM50543032 CHEMBL4645570

SMILES COc1ncc(cc1NS(C)(=O)=O)N1CCOc2ccc(CN(C)C)cc12

InChI Key InChIKey=SAHCNYAOSGATSF-UHFFFAOYSA-N

Data  5 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50543032   

LigandPNGBDBM50543032(CHEMBL4645570)
Affinity DataIC50:  631nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50543032(CHEMBL4645570)
Affinity DataKd:  251nMAssay Description:Binding affinity to PI3Kdelta (unknown origin) by SPR based van't Hoff analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50543032(CHEMBL4645570)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of PI3Kdelta in whole blood (unknown origin) assessed as reduction in cytostim-induced IFNgamma productionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50543032(CHEMBL4645570)
Affinity DataIC50:  7.94E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
LigandPNGBDBM50543032(CHEMBL4645570)
Affinity DataIC50:  2.51E+4nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
LigandPNGBDBM50543032(CHEMBL4645570)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed