BDBM5223 US8530490, 130
SMILES: OC(C1CCCN1S(=O)(=O)CCCn1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccccc1
InChI Key: InChIKey=NBGXNYZRJDHHHU-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase) (Homo sapiens (Human)) | BDBM5223![]() (US8530490, 130) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar | PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Taiho Pharmaceutical Co., Ltd US Patent | Assay Description The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-... | US Patent US8530490 (2013) BindingDB Entry DOI: 10.7270/Q25H7DX2 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |