BDBM53358 3-(furan-2-carbonyl)-4-hydroxy-2-(4-methylsulfanylphenyl)-1-(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)-2H-pyrrol-5-one::3-(furan-2-ylcarbonyl)-2-(4-methylsulfanylphenyl)-1-(5-methylsulfanyl-1,3,4-thiadiazol-2-yl)-4-oxidanyl-2H-pyrrol-5-one::3-[2-furanyl(oxo)methyl]-4-hydroxy-2-[4-(methylthio)phenyl]-1-[5-(methylthio)-1,3,4-thiadiazol-2-yl]-2H-pyrrol-5-one::4-(2-furoyl)-3-hydroxy-5-[4-(methylthio)phenyl]-1-[5-(methylthio)-1,3,4-thiadiazol-2-yl]-3-pyrrolin-2-one::MLS001140617::SMR000650457::cid_4905842

SMILES CSc1nnc(s1)N1C(C(C(=O)c2ccco2)C(=O)C1=O)c1ccc(SC)cc1

InChI Key InChIKey=LRWUUTZUVUTMSB-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 53358   

TargetPOsterior Segregation(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53358(3-(furan-2-carbonyl)-4-hydroxy-2-(4-methylsulfanyl...)
Affinity DataEC50:  6.79E+3nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
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TargetZinc finger protein mex-5(Caenorhabditis elegans)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53358(3-(furan-2-carbonyl)-4-hydroxy-2-(4-methylsulfanyl...)
Affinity DataEC50:  1.64E+4nMAssay Description:Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...More data for this Ligand-Target Pair
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TargetEndoribonuclease toxin MazF(Escherichia coli str. K-12 substr. MG1655)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53358(3-(furan-2-carbonyl)-4-hydroxy-2-(4-methylsulfanyl...)
Affinity DataEC50: >9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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TargetTropomyosin alpha-1 chain(Sus scrofa)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM53358(3-(furan-2-carbonyl)-4-hydroxy-2-(4-methylsulfanyl...)
Affinity DataEC50:  279nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
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TargetEndoribonuclease toxin MazF(Escherichia coli str. K-12 substr. MG1655)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM53358(3-(furan-2-carbonyl)-4-hydroxy-2-(4-methylsulfanyl...)
Affinity DataEC50: >9.90E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
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TargetGenome polyprotein(Hepatitis C virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM53358(3-(furan-2-carbonyl)-4-hydroxy-2-(4-methylsulfanyl...)
Affinity DataIC50:  4.87E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay