BDBM53422 2,4-Dicyclohexyl-6-methoxy-quinazoline::2,4-dicyclohexyl-6-methoxyquinazoline::MLS001050047::Menadione, 10::SMR000469610::cid_23640941

SMILES COc1ccc2nc(nc(C3CCCCC3)c2c1)C1CCCCC1

InChI Key InChIKey=VIXXSPHYTXZGKX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 53422   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53422(2,4-Dicyclohexyl-6-methoxy-quinazoline | 2,4-dicyc...)
Affinity DataIC50:  4.70E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53422(2,4-Dicyclohexyl-6-methoxy-quinazoline | 2,4-dicyc...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53422(2,4-Dicyclohexyl-6-methoxy-quinazoline | 2,4-dicyc...)
Affinity DataIC50:  1.26E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed