BDBM53442 (7-chloranyl-3,5-dimethyl-1-benzofuran-2-yl)-(4-oxidanyl-4-phenyl-piperidin-1-yl)methanone::(7-chloro-3,5-dimethyl-1-benzofuran-2-yl)-(4-hydroxy-4-phenylpiperidin-1-yl)methanone::(7-chloro-3,5-dimethyl-2-benzofuranyl)-(4-hydroxy-4-phenyl-1-piperidinyl)methanone::(7-chloro-3,5-dimethyl-benzofuran-2-yl)-(4-hydroxy-4-phenyl-piperidino)methanone::1-[(7-chloro-3,5-dimethyl-1-benzofuran-2-yl)carbonyl]-4-phenylpiperidin-4-ol::MLS001008702::O-acyl oxime isatin derivative, 31::SMR000495189::cid_23723572

SMILES Cc1c(oc2c(Cl)cc(C)cc12)C(=O)N1CCC(O)(CC1)c1ccccc1

InChI Key InChIKey=HPGTZOYRBXTCJE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 53442   

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53442((7-chloranyl-3,5-dimethyl-1-benzofuran-2-yl)-(4-ox...)
Affinity DataIC50:  1.20E+3nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM53442((7-chloranyl-3,5-dimethyl-1-benzofuran-2-yl)-(4-ox...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53442((7-chloranyl-3,5-dimethyl-1-benzofuran-2-yl)-(4-ox...)
Affinity DataIC50:  2.50E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed