BDBM5469 6-(3-methylbutoxy)-9H-purin-2-amine::CHEMBL269872::O6-Substituted Guanine Deriv. 11

SMILES CC(C)CCOc1nc(N)nc2nc[nH]c12

InChI Key InChIKey=OYBZHCFDWLRUHE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 5469   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle

LigandPNGBDBM5469(6-(3-methylbutoxy)-9H-purin-2-amine | CHEMBL269872...)
Affinity DataIC50:  2.10E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM5469(6-(3-methylbutoxy)-9H-purin-2-amine | CHEMBL269872...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of CDK1/Cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5469(6-(3-methylbutoxy)-9H-purin-2-amine | CHEMBL269872...)
Affinity DataIC50: >1.00E+6nMAssay Description:concentration required to reduce AGT activity to 50% of control rate in HT-29 cell extract.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Newcastle

LigandPNGBDBM5469(6-(3-methylbutoxy)-9H-purin-2-amine | CHEMBL269872...)
Affinity DataIC50:  2.60E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed