BDBM5471 6-ethoxy-9H-purin-2-amine::CHEMBL406419::O6-Substituted Guanine Deriv. 2

SMILES CCOc1nc(N)nc2nc[nH]c12

InChI Key InChIKey=SFXXRVSPZSOREJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5471   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University of Newcastle

LigandPNGBDBM5471(6-ethoxy-9H-purin-2-amine | CHEMBL406419 | O6-Subs...)
Affinity DataAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylated-DNA--protein-cysteine methyltransferase(Homo sapiens (Human))
Newcastle University

Curated by ChEMBL
LigandPNGBDBM5471(6-ethoxy-9H-purin-2-amine | CHEMBL406419 | O6-Subs...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of AGT activity to 50% of control rate in HT-29 cell extractMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University of Newcastle

LigandPNGBDBM5471(6-ethoxy-9H-purin-2-amine | CHEMBL406419 | O6-Subs...)
Affinity DataAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed