BDBM5534 2-(3,5-Dichloroanilino)-6-cyclohexylmethyloxypurine::6-(cyclohexylmethoxy)-N-(3,5-dichlorophenyl)-9H-purin-2-amine::O6-Cyclohexylmethylguanine deriv. 18

SMILES Clc1cc(Cl)cc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)c1

InChI Key InChIKey=YCWZCGXPKQMJLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5534   

TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Newcastle

LigandPNGBDBM5534(2-(3,5-Dichloroanilino)-6-cyclohexylmethyloxypurin...)
Affinity DataIC50:  1.20E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle

LigandPNGBDBM5534(2-(3,5-Dichloroanilino)-6-cyclohexylmethyloxypurin...)
Affinity DataIC50:  1.30E+4nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed