BDBM5541 4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phenol::6-Cyclohexylmethoxy-2-(4 -hydroxyanilino)purine::CHEMBL340813::O6-Cyclohexylmethylguanine deriv. 25

SMILES Oc1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1

InChI Key InChIKey=RFSDQDHHBKYQOD-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5541   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle

LigandPNGBDBM5541(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phen...)
Affinity DataIC50:  94nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM5541(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phen...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human Thr160-phospho CDK2/CyclinAMore data for this Ligand-Target Pair
TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Newcastle

LigandPNGBDBM5541(4-{[6-(cyclohexylmethoxy)-9H-purin-2-yl]amino}phen...)
Affinity DataIC50:  69nMAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair