BDBM5589 2-arylamino-pyrimidine deriv. 8a::4-{[4-amino-6-(cyclohexylmethoxy)pyrimidin-2-yl]amino}benzamide

SMILES NC(=O)c1ccc(Nc2nc(N)cc(OCC3CCCCC3)n2)cc1

InChI Key InChIKey=KVCWGWGQOGKCFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5589   

TargetCyclin-A2 [171-432]/Cyclin-dependent kinase 2(Homo sapiens (Human))
University Of Newcastle

LigandPNGBDBM5589(2-arylamino-pyrimidine deriv. 8a | 4-{[4-amino-6-(...)
Affinity DataIC50:  5.90E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
University Of Newcastle

LigandPNGBDBM5589(2-arylamino-pyrimidine deriv. 8a | 4-{[4-amino-6-(...)
Affinity DataIC50:  6.30E+4nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate histone H1 in the presence of 12.5 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which inhibits ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed