BDBM5622 3-Cyclopropyl-5-(acetamido)indeno[1,2-c]pyrazol-4-one::Indenopyrazole 13e::N-{3-cyclopropyl-4-oxo-2H,4H-indeno[1,2-c]pyrazol-5-yl}acetamide

SMILES CC(=O)Nc1cccc2-c3n[nH]c(C4CC4)c3C(=O)c12

InChI Key InChIKey=HRVSQBQPYCLNDW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 5622   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5622(3-Cyclopropyl-5-(acetamido)indeno[1,2-c]pyrazol-4-...)
Affinity DataIC50:  480nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM5622(3-Cyclopropyl-5-(acetamido)indeno[1,2-c]pyrazol-4-...)
Affinity DataIC50: >3.70E+3nMAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 50 uM ATP/[gamma-32P] ATP, and capturing the 32-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed