BDBM5777 4-butoxy-5-[(4-chloro-2,6-difluorophenyl)carbonyl]-1H-pyrazolo[3,4-b]pyridine::SQ-67563 Analog 21i::pyrazolo[3,4-b]pyridine deriv.
SMILES CCCCOc1c(cnc2[nH]ncc12)C(=O)c1c(F)cc(Cl)cc1F
InChI Key InChIKey=KHLSGMMGWBAAOY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 5777
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 13nMpH: 8.0 T: 2°CAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 310nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description: The enzyme was assayed with substrate in the presence of 25 uM ATP/[gamma-33P] ATP and test compound. Dose response curves were generated to determ...More data for this Ligand-Target Pair