BDBM59611 1'-acetyl-6-amino-3-[(4-methylphenyl)sulfanylmethyl]spiro[2H-pyrano[2,3-c]pyrazole-4,4'-piperidine]-5-carbonitrile::1'-acetyl-6-amino-3-[(p-tolylthio)methyl]spiro[2H-pyrano[2,3-c]pyrazole-4,4'-piperidine]-5-carbonitrile::1'-acetyl-6-amino-3-[[(4-methylphenyl)thio]methyl]-5-spiro[2H-pyrano[2,3-c]pyrazole-4,4'-piperidine]carbonitrile::6-azanyl-1'-ethanoyl-3-[(4-methylphenyl)sulfanylmethyl]spiro[2H-pyrano[2,3-c]pyrazole-4,4'-piperidine]-5-carbonitrile::MLS000080046::SMR000036525::cid_660127

SMILES CC(=O)N1CCC2(CC1)C(C#N)C(=N)Oc1[nH]nc(CSc3ccc(C)cc3)c21

InChI Key InChIKey=WKFYBVJZPVGHNP-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 59611   

TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM59611(1'-acetyl-6-amino-3-[(4-methylphenyl)sulfanylmethy...)
Affinity DataIC50:  2.11E+4nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM59611(1'-acetyl-6-amino-3-[(4-methylphenyl)sulfanylmethy...)
Affinity DataEC50:  2.90E+3nMAssay Description:Keywords: GFP-RecA intein, protein splicing, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, whi...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM59611(1'-acetyl-6-amino-3-[(4-methylphenyl)sulfanylmethy...)
Affinity DataEC50:  2.34E+4nMAssay Description:Keywords: GFP, refolding, reducing reagent, GFP fluorescence Assay Overview: M. tuberculosis harbors three inteins, which interrupt the DnaB, RecA, a...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay