BDBM60920 thionicotinamide

SMILES NC(=S)c1cccnc1

InChI Key InChIKey=XQWBMZWDJAZPPX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 60920   

TargetPolyphenol oxidase 2(White button mushroom)
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM60920(thionicotinamide)
Affinity DataKi:  4.30E+3nMAssay Description:Non-competitive inhibition of mushroom tyrosinase using L-tyrosine as substrate by Lineweaver-Burk plots analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNicotinamide N-methyltransferase(Human)
Utrecht University

LigandPNGBDBM60920(thionicotinamide)
Affinity DataKi:  6.60E+7nM ΔG°:  -1.67kcal/molepH: 8.6 T: 37°CAssay Description:Enzyme activity assays were performed as previously described with NNMT (16.25 ug/mL, 550 nM) in 50 mM Tris buffer (pH 8.6) containing 1 mM DTT (all ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPolyphenol oxidase 2(White button mushroom)
Kyungpook National University

Curated by ChEMBL
LigandPNGBDBM60920(thionicotinamide)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed