BDBM6329 2-Aminoquinazoline 7::7-methoxy-8-(propan-2-yl)-N-[4-(pyrrolidin-1-yl)phenyl]quinazolin-2-amine
SMILES COc1ccc2cnc(Nc3ccc(cc3)N3CCCC3)nc2c1C(C)C
InChI Key InChIKey=AWFQXBDHAKLADX-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 6329
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Naeja Pharmaceutical
Naeja Pharmaceutical
Affinity DataIC50: >5.00E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1 [L188C](Homo sapiens (Human))
Naeja Pharmaceutical
Naeja Pharmaceutical
Affinity DataIC50: 560nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 25 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:The enzyme was assayed with substrate GST- retinoblastoma in the presence of 12 uM ATP/[gamma-32P] ATP. IC50 is the inhibitor concentration, which in...More data for this Ligand-Target Pair