BDBM6396 6-(5-aminopyridin-3-yl)-N-(3-chlorophenyl)pyrazin-2-amine::Pyrazine-Pyridine Biheteroaryl 37::[6-(5-Amino-pyridin-3-yl)-pyrazin-2-yl]-(3-chloro-phenyl)-amine

SMILES Nc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=DJAHLZXHKVPSHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6396   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6396(6-(5-aminopyridin-3-yl)-N-(3-chlorophenyl)pyrazin-...)
Affinity DataIC50:  1.16E+3nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6396(6-(5-aminopyridin-3-yl)-N-(3-chlorophenyl)pyrazin-...)
Affinity DataIC50: >1.00E+4nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed