BDBM6415 4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyridin-3-yl)amino]butanoic acid::4-{5-[6-(3-Chloro-phenylamino)-pyrazin-2-yl]-pyridin-3-ylamino}-butyric acid::Pyrazine-Pyridine Biheteroaryl 61

SMILES OC(=O)CCCNc1cncc(c1)-c1cncc(Nc2cccc(Cl)c2)n1

InChI Key InChIKey=UVRBDUNZSLJHHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 6415   

TargetVascular endothelial growth factor receptor 2(Rattus norvegicus (rat))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6415(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)
Affinity DataIC50:  568nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6415(4-[(5-{6-[(3-chlorophenyl)amino]pyrazin-2-yl}pyrid...)
Affinity DataIC50:  5.22E+3nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed