BDBM64280 5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide::5-chloro-2-(4-fluorobenzyl)sulfonyl-N-(5-isopropyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide::5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)-4-pyrimidinecarboxamide::5-chloro-2-[(4-fluorophenyl)methylsulfonyl]-N-(5-propan-2-yl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide::MLS001116206::SMR000625775::cid_16446399

SMILES CC(C)c1nnc(NC(=O)c2nc(ncc2Cl)S(=O)(=O)Cc2ccc(F)cc2)s1

InChI Key InChIKey=LFJWSGCNKPRHNB-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 64280   

TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM64280(5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(...)
Affinity DataEC50:  3.33E+3nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPotassium voltage-gated channel subfamily KQT member 2(Rattus norvegicus)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(...)
Affinity DataEC50:  4.47E+3nMAssay Description:BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetProtein RecA(Mycobacterium tuberculosis H37Rv)
Southern Research Specialized Biocontainment Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(...)
Affinity DataIC50:  5.38E+4nMAssay Description:Southern Research's Specialized Biocontainment Screening Center (SRSBSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Librarie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTumor necrosis factor receptor superfamily member 10B(Homo sapiens (Human))
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM64280(5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(...)
Affinity DataEC50: >1.25E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPerilipin-1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(...)
Affinity DataIC50:  2.84E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPerilipin-5(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(...)
Affinity DataIC50:  1.94E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM64280(5-chloranyl-2-[(4-fluorophenyl)methylsulfonyl]-N-(...)
Affinity DataIC50:  4.69E+3nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay