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BDBM65552 Synthesized Sulfanylacrylonitril Derivatives 4

SMILES: CS\C(Nc1ccccc1)=C(\C#N)S(=O)(=O)c1ccc(Cl)cc1

InChI Key: InChIKey=QEVYKAJXMYQLIG-NXVVXOECSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 65552   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP-4-A phosphorylase


()
BDBM65552
PNG
(Synthesized Sulfanylacrylonitril Derivatives 4)
Show SMILES CS\C(Nc1ccccc1)=C(\C#N)S(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C16H13ClN2O2S2/c1-22-16(19-13-5-3-2-4-6-13)15(11-18)23(20,21)14-9-7-12(17)8-10-14/h2-10,19H,1H3/b16-15-
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/a8.0n/a



University of Konstanz



Assay Description
Dose response curves against Rv2613c with 1 as the substrate for derivatives 5 and 18. 8 nM of Rv2613c were preincubated in buffer (20 mM Tris-HCl (p...


ACS Chem Biol 12: 2682-2689 (2017)


Article DOI: 10.1021/acschembio.7b00653
BindingDB Entry DOI: 10.7270/Q2CV4FW6
More data for this
Ligand-Target Pair